- Anett Kontaveit (6) defeated Katerina Siniakova 6-2 6-3
- Clara Tauson defeated Astra Sharma 6-3 6-4
- Ana Konjuh defeated Shelby Rogers 4-6 6-3 7-5
- Danielle Collins (27) defeated qualifier Caroline Dolehide 6-1 6-3
- Elise Mertens (19) defeated Vera Zvonareva 6-4 7-5
- Irina-Camelia Begu defeated Oceane Dodin 2-6 7-5 6-3
- Zhang Shuai defeated Viktorija Golubic 6-3 6-4
- Elena Rybakina (12) defeated Zarina Diyas 6-7(3) 7-6(3) 6-1
- Simona Halep (14) defeated Magdalena Frech 6-4 6-3
- Beatriz Haddad Maia defeated qualifier Katie Volynets 3-6 6-2 6-3
- Danka Kovinic defeated qualifier Jang Su-jeong 6-3 2-6 6-4
- Emma Raducanu (17) defeated Sloane Stephens 6-0 2-6 6-1
- Tamara Zidansek (29) defeated Arantxa Rus 3-6 6-3 7-6(10-8)
- Heather Watson defeated Mayar Sherif 6-3 5-7 6-2
- Alizé Cornet defeated qualifier Viktoriya Tomova 6-3 6-3
- Garbiñe Muguruza (3) defeated Clara Burel 6-3 6-4
- Iga Swiatek (7) defeated qualifier Harriet Dart 6-3 6-0
- Rebecca Peterson defeated wildcard Daria Saville 6-2 6-3
- Magda Linette defeated Anastasija Sevastova 6-4 7-5
- Daria Kasatkina (25) defeated qualifier Stefanie Voegele 6-3 6-1
- Sorana Cirstea defeated Petra Kvitova (20) 6-2 6-2
- Kristina Kucova defeated Misaki Doi 6-3 7-5
- Wildcard Samantha Stosur defeated wildcard Robin Anderson 6-7(5) 6-3 6-3
- Anastasia Pavlyuchenkova (10) defeated Anna Bondar 6-2 6-1
- Kaia Kanepi defeated Angelique Kerber (16) 6-4 6-3
- Marie Bouzkova defeated qualifier Rebecca Marino 6-1 6-3
- Qualifier Hailey Baptiste defeated Caroline Garcia 4-6 7-6(4) 6-3
- Wildcard Maddison Inglis defeated Leylah Fernandez (23) 6-4 6-2
- Marketa Vondrousova (31) defeated wildcard Priscilla Hon 6-2 6-3
- Liudmila Samsonova defeated qualifier Emina Bektas 7-5 6-4
- Wang Xinyu defeated Ann Li 7-6(5) 6-3
- Aryna Sabalenka (2) defeated wildcard Storm Sanders 5-7 6-3 6-2
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