WTA - Prague 1R start

First round commenced in Prague.

2021 Livesport Prague Open - a WTA 250 tournament, on Hard, in Prague, Czech Republic, 12-18 July 2021.

Event held last year from 10-16 August 2020 due to COVID-19.

2020 champion (not defending):

Simona Halep (1) who defeated Elise Mertens (3) 6-2 7-5

The following players withdrew after the main draw was published:

- Sixth seed Hsieh Su-wei, replaced by lucky loser Conny Perrin, due to a hip injury 

Greet Minnen was instated as ninth seed and moved in the draw to the spot previously occupied by Hsieh Su-wei.

- Third seed Marketa Vondrousova, replaced by lucky loser Liang En-Shuo, due to a thigh injury 

- Elena-Gabriela Ruse, replaced by lucky loser Anastasia Gasanova, due to a scheduling change 

First round results:

- Qualifier Rebecca Sramkova defeated Petra Kvitová (1) 7-6(5) 3-6 6-4

- Qualifier Asia Muhammad defeated Lizette Cabrera 3-6 6-2 6-2

- Greet Minnen (9) defeated Giulia Gatto-Monticone 6-0 4-6 6-1

- Nina Stojanovic (7) defeated Vitalia Diatchenko 6-7(5) 6-1 6-3

- Grace Min defeated wildcard Samantha Stosur 6-3 2-6 6-3

- Tereza Smitkova defeated Maddison Inglis 6-2 6-2