ATP - Madrid round of sixteen

Round of sixteen completed and quarter finals set in Madrid.

2021 Mutua Madrid Open - an ATP Masters 1000 tournament, on Clay, in Madrid, Spain, 2-9 May 2021.

Event not held last year due to COVID-19.

2019 champion (not defending):

Novak Djokovic (1) who defeated Stefanos Tsitsipas (8) 6-3 6-4

Round of sixteen results:

Rafael Nadal (1) defeated qualifier Alexei Popyrin 6-3 6-3

Alexander Zverev (5) defeated Daniel Evans 6-3 7-6(3)

Dominic Thiem (3) defeated Alex de Minaur 7-6(7) 6-4

John Isner defeated Andrey Rublev (6) 7-6(4) 3-6 7-6(4)

Alexander Bublik defeated Aslan Karatsev 6-4 6-3

Casper Ruud defeated Stefanos Tsitsipas (4) 7-6(4) 6-4

Matteo Berrettini (8) defeated qualifier Federico Delbonis 7-6(4) 6-4

Cristian Garín (16) defeated Daniil Medvedev (2) 6-4 6-7(2) 6-1

Quarter final match ups 

Rafael Nadal (1) v Alexander Zverev (5)

Dominic Thiem (3) v John Isner 

Alexander Bublik v Casper Ruud 

Matteo Berrettini (8) v Cristian Garin (16)