US Open - Men’s Singles 2R start

Day Three - Second round commenced at the 2022 US Open.

Including completion of unfinished rain interrupted first round matches from previous day

2022 US Open, on Hard, in New York City, New York, USA, 29 August - 11 September 2022.

Defending champion:

Daniil Medvedev (2) who defeated Novak Djokovic (1) 6-4 6-4 6-4.

First round results:

- Roberto Carballes Baena defeated Jaume Munar 6-1 6-3 4-6 6-2 after play resumed from previous day

- Jason Kubler defeated Mikael Ymer 5-7 6-4 6-2 6-4 after play resumed from previous day

Second round results:

- Daniil Medvedev (1) defeated Arthur Rinderknech 6-2 7-5 6-3

- Qualifier Wu Yibing defeated Nuno Borges 6-7(3) 7-6(4) 4-6 6-4 6-4

- Nick Kyrgios (23) defeated Benjamin Bonzi 7-6(3) 6-4 4-6 6-4

- Wildcard J.J. Wolf defeated Alejandro Tabilo 4-6 7-5 6-4 6-3

- Pablo Carreno Busta (12) defeated Alexander Bublik 4-6 6-4 6-3 7-6(5)

- Alex de Minaur (18) defeated Cristian Garin 6-3 6-0 4-6 6-2

- Karen Khachanov (27) defeated Thiago Monteiro 6-3 6-3 5-7 6-4

- Jack Draper defeated Felix Auger-Aliassime (6) 6-4 6-4 6-4

- Qualifier Daniel Elahi Galan defeated Jordan Thompson 6-3 2-6 3-6 6-4 6-3

- Alejandro Davidovich Fokina defeated Marton Fucsovics 7-6(3) 5-7 3-6 6-0 7-6(10-3)

- Andy Murray defeated wildcard Emilio Nava 5-7 6-3 6-1 6-0

- Matteo Berrettini (13) defeated lucky loser Hugo Grenier 2-6 6-1 7-6(4) 7-6(7)

- Pedro Cachin defeated qualifier Brandon Holt 1-6 2-6 6-1 7-6(1) 7-6(10-6)

- Lucky loser Corentin Moutet defeated Botic van de Zandschulp (21) 6-4 1-6 6-2 6-4

- Tommy Paul (29) defeated Sebastian Korda 6-0 3-6 4-6 6-3 6-4

- Casper Ruud (5) defeated Tim van Rijthoven 6-7(4) 6-4 6-4 6-4