WTA - Madrid 1R start

First round commenced in Madrid.

2021 Mutual Madrid Open - a WTA 1000 tournament, on Clay, in Madrid, Spain, 29 April - 9 May 2021.

Event not held last year due to COVID-19.

Defending champion (2019):

Kiki Bertens (7) who defeated Simona Halep (3) 6-4 6-4

10th seed Garbiñe Muguruza withdrew after the main draw was published due to a leg injury, and was replaced by lucky loser Danka Kovinic.

First round results:

- Ashleigh Barty (1) defeated Shelby Rogers 6-2 6-1

- Qualifier Tamara Zidansek defeated lucky loser Hsieh Su-Wei 6-2 6-4

- Laura Siegemund defeated qualifier Kateryna Kozlova 6-4 6-2

- Iga Swiatek (14) defeated Alison Riske 6-1 6-1

- Petra Kvitová (9) defeated Marie Bouzkova 6-2 2-3 (retired)

- Angelique Kerber defeated Marketa Vondrousova 7-6(5) 6-1

- Veronika Kudermetova defeated Elena Vesnina 6-1 6-4

- Kiki Bertens (7) defeated wildcard Victoria Jimenez Kasintseva 6-4 6-0

- Jil Teichmann defeated Elina Svitolina (4) 2-6 6-4 7-6(5)

- Wildcard Paula Badosa defeated Barbora Krejcikova 6-1 7-5

- Qualifier Anastasija Sevastova defeated qualifier Ana Bogdan 6-0 6-3

- Johanna Konta (15) defeated Yulia Putintseva 6-4 6-2

- Sloane Stephens defeated lucky loser Danka Kovinic 6-4 6-1

- Ons Jabeur defeated Yaroslava Shvedova 6-2 6-3

- Qualifier Bernarda Pera defeated Petra Martic 6-3 6-2

- Belinda Bencic (8) defeated qualifier Kristina Mladenovic 6-4 6-2