The following players withdrew after entering but before the main draw was published:
- Irina-Camelia Begu replaced by Leylah Fernandez
- Anna Blinkova replaced by Timea Babos
- Danielle Collins replaced by Martina Trevisan
- Fiona Ferro replaced by Anastasia Potapova
- Polona Hercog replaced by Nao Hibino
- Kaia Kanepi replaced by Camila Giorgi
- Anett Kontaveit replaced by Andrea Petkovic
- Barbora Krejcikova replaced by Danka Kovinic
- Ann Li replaced by Misaki Doi
- Jelena Ostapenko replaced by Christina McHale
- Anastasia Pavlyuchenkova replaced by Tsvetana Pironkova
- Jessica Pegula replaced by Zarina Diyas
- Rebecca Peterson replaced by Renata Zarazua
- Maria Sakkari replaced by Francesca Di Lorenzo
- Laura Siegemund replaced by Liudmila Samsonova
- Katerina Siniakova replaced by Lauren Davis
- Jil Teichmann replaced by Madison Brengle
- Heather Watson replaced by Caty McNally
Fourth seed, Kiki Bertens, withdrew after the main draw was published, due to an achilles injury, and was replaced by lucky loser Wang Xinyu.
Ninth seed, Marketa Vondrousova, moved to the spot Bertens occupied in the draw, and received the first round bye that Bertens had been given.
Marie Bouzkova was instated as 17th seed.
Ashleigh Barty, world number 1, is top seed.
The other 15 seeds are all in the top 55
The top eight seeds have first round byes.
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