ATP - Barcelona 2R complete

Second round completed in Barcelona.

2021 Barcelona Open Banco Sabadell - an ATP 500 tournament, on Clay, in Barcelona, Spain, 19-25 April 2021.

Event not held last year due to COVID-19.

2019 champion (not defending):

Dominic Thiem (3) who defeated Daniil Medvedev (7) 6-4 6-0

Casper Ruud, 15th seed, withdrew after the main draw was published due to an arm injury, and was replaced by lucky loser Federico Gaio.

Adrian Mannarino was instated as 17th seed, moved into the spot previously occupied by Ruud in the draw, inheriting a first round bye.

Second round results:

- Rafael Nadal (1) defeated qualifier Ilya Ivashka 3-6 6-2 6-4

- Kei Nishikori defeated Cristian Garin (13) 7-6(5) 4-6 6-1

- Diego Schwartzman (4) defeated Frances Tiafoe 3-6 7-5 6-1

- Corentin Moutet defeated Daniel Evans (16) 6-4 5-7 6-3

- Qualifier Bernabe Zapata Miralles defeated Fabio Fognini (9) 6-0 4-4 (defaulted)

- Pablo Carreno Busta (6) defeated Jordan Thompson 6-4 6-0

- Albert Ramos-Vinolas defeated Adrian Mannarino (17) 6-4 6-4

- Wildcard Andrey Rublev (3) defeated lucky loser Federico Gaio 6-4 6-3

- Felix Auger-Aliassime (10) defeated wildcard Lorenzo Musetti 4-6 6-3 6-0

- Alex de Minaur (14) defeated Alexander Bublik 7-6(3) 6-2

- Stefanos Tsitsipas (2) defeated wildcard Jaume Munar 6-0 6-2