Defending champion:
Alexander Zverev (1) who defeated Alex de Minaur 6-2 6-4
The following players withdrew after entering but before the main draw was published:
- Tomas Berdych replaced by Marius Copil
- Gaël Monfils replaced by Alexander Bublik
- Kei Nishikori replaced by Bradley Klahn
- Sam Querrey replaced by Malek Jaziri
- Denis Shapovalov replaced by Lloyd Harris
The following players withdrew after the main draw was published:
- Ugo Humbert replaced by lucky loser Ilya Ivashka
- Bernard Tomic replaced by lucky loser Peter Gojowczyk
Stefanos Tsitsipas, world number 6, is top seed.
The other seeds are all in the top 40
All sixteen seeds have first round byes
First round results
- Wildcard Tommy Paul defeated Denis Kudla 6-0 6-4
- Qualifier Marc Polmans defeated Malek Jaziri 6-2 6-4
- Hubert Hurkacz defeated qualifier Donald Young 6-1 6-4
- Adrian Mannarino defeated lucky loser Ilya Ivashka 7-6(3) 6-3
- Marius Copil defeated qualifier Mikael Torpegaard 6-1 5-7 6-3
- Alexander Bublik defeated Bradley Klahn 7-6(5) 6-3
- Wildcard Björn Fratangelo defeated Ivo Karlovic 6-4 6-7(14) 7-6(5)
- Qualifier Tim Smyczek defeated Matthew Ebden 6-4 6-4
- Lloyd Harris defeated Ricardas Berankis 4-6 6-3 6-1
- Jo-Wilfried Tsonga defeated qualifier Brayden Schnur 6-4 7-6(2)
- Jordan Thompson defeated wildcard Jack Sock 7-5 6-3
- Miomir Kecmanovic defeated Alexei Popyrin 7-6(6) 6-3
- Nick Kyrgios defeated qualifier Thai-Son Kwiatkowski 7-5 6-4
- Yoshihito Nishioka defeated Daniel Evans 6-4 6-1
- Reilly Opelka defeated wildcard Christopher Eubanks 6-4 7-6(3)
- Lucky loser Peter Gojowczyk defeated Andrey Rublev 7-6(6) 4-6 7-6(2)
Second round results
- Marin Cilic (5) defeated Marius Copil 7-6(4) 7-6(4)
- Frances Tiafoe (16) defeated Alexander Bublik 6-1 7-6(5)
- Daniil Medvedev (3) defeated wildcard Björn Fratangelo 6-3 6-4
- Kyle Edmund (13) defeated Lloyd Harris 6-1 6-4
- Jo-Wilfried Tsonga defeated Karen Khachanov (2) 6-4 2-6 7-5
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